Njengoko ukubekwa wedwa kwezentlalo e-United States kuye kwanda phakathi kwabantu abadala, uphononongo olutsha lubonisa ikhonkco elibonakalayo phakathi kwesithukuthezi kunye nomngcipheko we-dementia, kunye neyona nto ibetha kakhulu kubantu baseMelika abamele inxalenye enkulu yabemi.
Kuphononongo olupapashwe nge-7 kaFebruwari kwi-Neurology, ijenali yezonyango ye-American Academy of Neurology, abaphandi bafumene ukonyuka okuphindwe kathathu kumngcipheko wokuba nesifo sengqondo esixhalabisayo phakathi kwabantu baseMelika ababodwa abangaphantsi kweminyaka engama-80 ubudala ebekulindeleke ukuba babenomngcipheko ophantsi. ngokusekelwe kwiminyaka yobudala kunye nemingcipheko yemfuza. Uphononongo luphinde lwafumanisa ukuba isithukuthezi sasinxulumene nomsebenzi wokulawula ompofu (oko kukuthi, iqela leenkqubo zengqondo ezibandakanya ukwenza izigqibo, ukucwangcisa, ukuguquguquka kwengqondo, kunye nokulawula ingqalelo) kunye noshintsho kwingqondo ebonisa ukuba sesichengeni kwi-Alzheimer's disease kunye ne-dementias ehambelana nayo ( ADRD).
"Olu pho nonongo lugxininisa ukubaluleka kwesizungu kunye nemiba yoxhulumaniso lwentlalo ekujonganeni nomngcipheko wethu wokukhula kwengqondo njengoko sikhula," utshilo umphenyi okhokelayo uJoel Salinas, MD, MBA, MSc, uLulu P. kunye noDavid J. Levidow uMncedisi onguNjingalwazi weNeurology. kwi-NYU Grossman School of Medicine kunye nelungu leSebe le-Neurology's Centre ye-Cognitive Neurology. “Ukuvuma iimpawu zobulolo kuwe nakwabanye, ukwakha nokugcina ubudlelwane obuxhasayo, ukubonelela ngenkxaso efuneka kakhulu kubantu kubomi bethu abaziva bengamalolo—ezi zibalulekile kumntu wonke. Kodwa zibaluleke kakhulu njengoko sibudala ukonyusa amathuba okuba silibazise okanye sithintele ukwehla kwengqondo. ”
I-Dementia ichaphazela ngaphezu kwe-6.2 yezigidi zabantu abadala e-United States, ngokwengxelo ekhethekileyo ye-2021 ye-Alzheimer's Association. Ukusukela oko kwaqala ubhubhani we-coronavirus, iimvakalelo zobulolo ziye zachaphazela abantu baseMelika abaqikelelwa kwizigidi ezingama-46, kwaye iimvakalelo zobulolo zafunyanwa kubantu abadala abaneminyaka engama-60 nangaphezulu.
UGqr. Salinas uthi: “Olu phononongo lusisikhumbuzo sokuba, ukuba sifuna ukubeka phambili impilo yengqondo, asikwazi ukuyibetha ngoyaba indima yeemeko zengqondo ezifana nobulolo kunye nentlalontle esihlala kuyo imihla ngemihla. Ngamanye amaxesha, eyona ndlela ilungileyo yokuzinyamekela kunye nabantu esibathandayo kukufikelela rhoqo kwaye ujonge-ukuvuma kwaye uvunywe.
UGqr. Salinas wongezelela ngelithi, “Sinokwabelana omnye nomnye xa siziva singamalolo, siyixabise indlela ubulolo obuxhaphake ngayo, size sivume ukuba ukupha nokucela inkxaso kunokuba nzima. Ngethamsanqa, ubulolo bunokunyangwa. Kwaye nangona sinokufuna ukuba sesichengeni kunye nokuyila ekufumaneni iindlela ezintsha zokunxibelelana, amathuba kukuba nesona senzo sincinci siya kuba sifanelekile. ”
Indlela Esiqhutywa Ngayo Isifundo
Ukusebenzisa idatha ye-retrospective ye-Poming-based Framingham Study (FS), abaphandi bahlaziywa abathathi-nxaxheba be-2,308 ababengenayo i-dementia kwisiseko, kunye ne-avareji yobudala be-73. Imilinganiselo ye-Neuropsychological kunye ne-MRI brain scans zafunyanwa kwiimviwo kwaye abathathi-nxaxheba babuzwa ukuba bavame kangakanani. ukuziva ulilolo kunye nezinye iimpawu ezidandathekisayo, njengokungaphumli okanye ukungakucaceli ukutya. Abathathi-nxaxheba baphinde bavavanyelwa ubukho bomngcipheko wemfuza wesifo i-Alzheimer ebizwa ngokuba yi-APOE ε4 allele. Lilonke, i-144 yabathathi-nxaxheba be-2,308 baxele ukuba banesithukuthezi iintsuku ezintathu okanye ngaphezulu kwiveki ephelileyo.
Abemi bophononongo bavavanywa kwisithuba seminyaka elishumi ngenxa yesifo sengqondo esiyingozi kusetyenziswa iindlela ezingqongqo zeklinikhi, kwaye i-329 yabathathi-nxaxheba be-2,308 baye bafumanisa ukuba banesifo. Phakathi kwabathathi-nxaxheba abali-144 ababodwa, abangama-31 baye baba nokuphazamiseka kwengqondo. Nangona kwakungekho nxulumano lubalulekileyo phakathi kwesithukuthezi kunye nesifo sengqondo esiyingozi kubathathi-nxaxheba abaneminyaka engama-80 ubudala okanye ngaphezulu, abathathi-nxaxheba abancinci abaneminyaka engama-60 ukuya kwe-79 ababenesithukuthezi babengaphezu kokuphindwe kabini ukuhlakulela isifo sengqondo esixhalabisayo. Ubulolo babunxulunyaniswa nengozi ephindwe kathathu eyongeziweyo phakathi kwabathathi-nxaxheba abancinci abangazange baphathe i-APOE ε4 allele.
Abaphandi bagqibe kwelokuba ukuphindaphindeka kathathu emngciphekweni kusenokwenzeka ukuba kunxulumene nonxulumano phakathi kwesithukuthezi kunye neempawu zokuqala zengqondo kunye ne-neuroanatomical ye-ADRD sesichengeni, ukuphakamisa iziphumo ezinokuthi zibekho kwimpilo yabemi kwiindlela ezijongwayo zobulolo. Iziphumo ezongezelelweyo zibonise ukuba isithukuthezi sasinxulumene nomsebenzi olawulayo ophantsi, umthamo ophantsi we-cerebral umthamo, kunye nokulimala okukhulu okumhlophe, okuyizibonakaliso zobuthathaka bokuncipha kwengqondo.
Ukongeza kuGqr. Salinas, abaphandi abavela kwiYunivesithi yaseBoston yezeMpilo yoLuntu, iBoston University School of Medicine, iYunivesithi yaseCalifornia Davis, kunye neBiggs Institute for Alzheimer's and Neurodeergenerative Diseases kwiYunivesithi yaseTexas Health Sciences Centre San Antonio nabo babandakanyeka. kwisifundo.
INTO ONOKUYITHATHA KWELI NQAKU:
- In the study published February 7 in Neurology, the medical journal of the American Academy of Neurology, researchers found a three-fold increase in risk of subsequent dementia among lonely Americans younger than 80 years old who would otherwise be expected to have a relatively low risk based on age and genetic risk factors.
- Njengoko ukubekwa wedwa kwezentlalo e-United States kuye kwanda phakathi kwabantu abadala, uphononongo olutsha lubonisa ikhonkco elibonakalayo phakathi kwesithukuthezi kunye nomngcipheko we-dementia, kunye neyona nto ibetha kakhulu kubantu baseMelika abamele inxalenye enkulu yabemi.
- “This study is a reminder that, if we want to prioritize brain health, we can’t ignore the role of psychosocial factors like loneliness and the social environments we live in day-to-day,”.
