Ngokuhambelana nesicwangciso, i-GoldenBiotech iya kungenisa ingxelo yokugqibela yohlalutyo lovavanyo lweklinikhi kunye namaxwebhu anxulumene ne-R & D kwi-US FDA ukufaka isicelo sogunyaziso lokusetyenziswa olungxamisekileyo (EUA) kwi-Antroquinonol (HOCENA®).
Olu lingo siSigaba se-2 esingacwangciswanga, esibumfama kabini, sophononongo olulawulwa yi-placebo ukuhlola ukhuseleko kunye nokusebenza kakuhle kwe-Antroquinonol kwizigulana ezilaliswe esibhedlele ezinenyumoniya ephakathi ukuya kwephakathi ngenxa ye-COVID-19 (isifo se-coronavirus SARS-CoV-2). Ngokwenyani, ulingo lukwabandakanya izigulana ezibukhali ze-ICU ezifuna inkxaso ye-oxygen. Emva kokugqitywa kwazo zonke iimvavanyo zokuhlola kunye nentlanganiso yeenqobo zokufaneleka, izigulane ziya kufumana i-100mg ye-Antroquinonol okanye i-placebo kabini ngosuku ngeentsuku ze-14 ngokudibanisa ne-Standard of Care (SoC) unyango ngokwemigaqo-nkqubo ye-SoC yendawo. Ulingo lwagqiba ukugaya abaguli abali-124 e-USA, ePeru naseArgentina apho ubhubhani omtsha ugqugqisile ngeentlobo ezahlukeneyo zosulelo lwe-SARS-CoV-2.
Idatha yolingo lweklinikhi ityhile:
1. IsiPhumo seSiphumo esiPhambili: ukubuyisela umlinganiselo [Ixesha lexesha: iintsuku ze-14] Umlinganiselo wezigulane eziphilileyo kwaye zikhululekile ekuphefumleni (umzekelo, akukho mfuneko yokungena komoya ongenayo, umoya ongeyena-invasive, i-oksijeni ephezulu, okanye i-ECMO) Usuku lwe-14.Isiphumo: Kwiqela le-Antroquinonol, umlinganiselo wokubuyisela wawuyi-97.9% ngosuku lokutyelela kwe-14. Ngaphezu koko, akukho kufa okanye ukungaphumeleli kokuphefumula kwafunyanwa kwiqela le-Antroquinonol ngosuku lwe-28 lokutyelela kunye nomlinganiselo wokubuyisela we-100%.
2. ImiGangatho yesiPhumo seSekondari:(a) Ubude bexesha lokuhlala kwe-ICU:Isiphumo: Ubude bexesha eliphakathi kwe-ICU lokuhlala kwiqela le-Antroquinonol lalimfutshane ngeentsuku ezi-9.5 kunelo kwiqela le-placebo. (b) Ubude bexesha lokulaliswa esibhedlele [ Ixesha elimiselweyo: iintsuku ze-28]: ixesha lokukhutshwa kwesigulane. Isiphumo: Ixesha eliphakathi kwesibhedlele laliyientsuku ze-4 kwiqela le-Antroquinonol. (c) Ixesha lokuphucula amanqaku e-2 [ Ixesha lexesha: iintsuku ze-28] : Inqaku lotshintsho lwezonyango njengoko lilinganiswe “yi-WHO COVID-19 Clinical Improvement Ordinal Scale”.Isiphumo: Ixesha eliphakathi lokufumana amanqaku ka-0 “kwi-WHO COVID-19 Clinical Improvement Ordinal Scale” yayiziintsuku ezingama-29 kwiqela le-antroquinonol.(d) Ixesha lokukhutshwa kwe-virological clearance [ Ixesha elimiselweyo: iintsuku ezingama-28]: zilinganiswa njengeentsuku zokufunda ukusuka ekuqaleni konyango ukuya kuvavanyo lokuqala olubi lwe-SARS-CoV-2 PCR.
Kuvavanyo lokhuseleko, idatha ibonise ukuba i-Antroquinonol ibonise ukunyamezela okulungileyo kunye neziphumo zokhuseleko.
