Isoyikiso esifihlakeleyo sokunqunyulwa kwemilenze esiNxulumene ne-Peripheral Artery Disease (PAD)

Iinkampani zeJanssen Pharmaceutical Companies zikaJohnson & Johnson namhlanje zibhengeze ukuqaliswa kweSave Legs. Guqula uBomi.™ Spot Peripheral Artery Disease Ngoku, inyathelo leminyaka emininzi elijolise ekudaleni ungxamiseko kunye nenyathelo lokujongana nesoyikiso esifihlakeleyo sokunqunyulwa kwelungu le-peripheral artery disease (PAD), kugxilwe ekuqaleni ekufikeleleni abantu abaMnyama baseMelika, abangaphezulu koku. kabini kunokwenzeka ukuba ichatshazelwe yi-PAD.1 Janssen uye wadibanisa imibutho ekhokelayo yobuchwephesha, iinkqubo zempilo kunye nemibutho yoluntu ukuqhubela phambili ukhathalelo olulinganayo lwabantu kunye noluntu olubekwe kumngcipheko owongeziweyo wesifo senhliziyo e-US.

Isifo senhliziyo - esaziwa ngokuba nesifo senhliziyo - yimbangela ehamba phambili yokufa kwi-US2 kwaye inokuchaphazela ngaphezu kwentliziyo nje.3 Imeko enye enzima ehlala ihlanjululwa kwaye iyancipha i-PAD, i-4 imeko eqhelekileyo yokujikeleza eyenza imithwalo yegazi imxinwa kwaye inciphisa ukuhamba kwegazi kumalungu, ngokuphindaphindiweyo imilenze. I-PAD ye-5 ichaphazela abantu abaqikelelwa kwi-20 yezigidi zaseMelika, i-6 kodwa kuphela malunga ne-8.5 yezigidi eziye zafunyaniswa.7 Ukuba ayishiywanga inganyangwa, i-PAD ingakhokelela kwiziganeko ezinzulu ezibandakanya ukuhlaselwa yintliziyo, ukubetha, ukuhlaselwa i-ischemia okanye ukunqunyulwa kwelungu lomzimba.5 

Abantu abamnyama baseMelika bafumana amazinga angafaniyo esifo senhliziyo, i-8 kwaye - ngenxa yamazinga aphezulu e-PAD asymptomatic, i-9 ukufikelela okuncinci kumgangatho wokunakekelwa kwe-vascular10 kunye nomngcipheko omkhulu wokulibaziseka ekunyamekelweni9 - ukuya kumaxesha amane ngaphezu kokuba abamhlophe baseMelika babe ne I-PAD-enxulumene nokunqunyulwa kwemilenze.10

“Nangona ukungalingani kwezempilo kudala kukho, iminyaka eliqela edlulileyo ibazise phambili kwingqiqo yethu ehlangeneyo. Abantu abaNtsundu baseMelika babekwe emngciphekweni omkhulu wokuphulukana nemilenze nobomi - into eyinyani sonke kufuneka sijongane nayo ngenkuthalo, utshilo uGqr Pernessa Seele *, uMseki kunye ne-CEO, i-Balm eGilead, Inc., intlangano yokholo ebandakanyeka ekupheliseni impilo. iyantlukwano. “Sikholelwa ukuba eyona ndlela isebenzayo yokuphelisa iyantlukwano eyothusayo yezempilo phakathi kwabantu abaNtsundu kukwenza ngenjongo, ezinzileyo nenemfesane lishishini lezempilo, impilo yoluntu kunye noluntu lwezenkolo.”

I-PAD yimbangela ehamba phambili yokunqunyulwa kwezitho e-US, i-10 kunye namazinga aqhubeka enyuka.11 Ukuqhawula i-PAD yingxaki ephazamisayo ye-PAD kwaye inxulunyaniswa nokufa okuphezulu, nangona kuthinteleka kakhulu. ukwanda komngcipheko wokufa, kunye neepesenti ezingama-10 zezigulane ezine-PAD ezinqunyulwe umlenze zifa kwiminyaka emithathu.70

Gcina Imilenze. Guqula uBomi.™ ineendawo ezintathu eziphambili ekugxilwe kuzo: ukuqhuba uphando, ukusebenzisana namaqabane anamandla, kunye nokuxhobisa abantu kunye noluntu.