Uvavanyo olukhawulezileyo lwe-COVID-19 ifundwa eFinland

Phakathi kophando lwesitofu sokulwa i I-coronavirus ye-COVID-19 ibango elimalunga namazwe angama-30, iFinland yazisa ngenqanaba layo lokuqhubela phambili kuvavanyo olukhawulezileyo lwezixhobo ze-COVID-19 zokuchonga intsholongwane eyingozi. Oku kuxeliwe nguMnu. Gianfranco Nitti, umbhaleli weFinnish "La Rondine" kunye nelungu le-Media Media Associatio, eRoma. Ingxelo ithi:

Ukwenza uvavanyo olukhawulezileyo noluthembekileyo lokuchonga esi sifo kwindyikitya yethu yeminyaka yokuqala kukuzinikela kweelebhu, izazinzulu kunye namaziko ophando kwihlabathi liphela. Yiyo le nto icetywayo eFinland e ukukhwela ibhayikhi entabeni, iZiko loPhando likaRhulumente, uPhuhliso kunye neZiko elitsha.

Ngabasebenzi abangaphezulu kwama-2,000 1942, kubandakanya inani elikhulu lezenzululwazi kunye nabaphandi, ikhuthaza ukukhula okuzinzileyo kwaye ijongane nemiceli mngeni mikhulu yexesha lethu ukuyiguqula ibe ngamathuba okukhula, inceda uluntu kunye neenkampani ukuba zikhule ngobugcisa bezobuchwepheshe. Yasekwa ngonyaka we-80, iyaqhayisa phantse iminyaka engama-XNUMX yamava kuphando olukumgangatho ophezulu nakwiziphumo zesayensi.

Iqela labaphandi beMeVac

Kwaye kanye kwi-VTT apho umsebenzi wawuqala kuhlobo olutsha lovavanyo olusekwe ekufumaneni ii-antigen zentsholongwane yentsholongwane ye-COVID-19. Injongo yovavanyo olukhawulezileyo kukubonelela ngoochwephesha bezempilo ngendlela echanekileyo, ekhawulezileyo nesebenzayo yokufumana usulelo lwe-coronavirus kwangoko ngovavanyo olukhawulezileyo lwe-COVID-19.

Uphuhliso lovavanyo olukhawulezileyo lwenziwa yi-VTT kunye neMeVac-Meilahti kwiziko lophando kwisitofu sokugonya. Le projekthi ikwafuna ngenkuthalo iinkampani zaseFinland ukuba zijoyine intsebenziswano.

Indlela yovavanyo olukhawulezileyo isekwe ekufumanekeni kweeantigens zentsholongwane kwiisampulu ze-nasopharyngeal kwaye iya kuvumela ukuxilongwa kwe-COVID-19 kwinqanaba lokuqala lesi sifo. Uvavanyo luyilelwe ukuba lwenziwe ngabaqeqeshi bezempilo- ubuncinci kwisigaba sokuqala. Nangona kunjalo, iziphumo ziya kubuyiselwa ngokukhawuleza okukhulu kuneemvavanyo esele zikhona, ngaphakathi kwemizuzu eli-15 okanye ngaphantsi.

Iprototype yesixhobo sokuchonga ngokukhawuleza

Uvavanyo olutsha olukhawulezayo lwe-COVID-19 nayo iya kuba ngexabiso eliphantsi kuneendlela zangoku zovavanyo. Uphuhliso lwe-Antibody sele luqalisile kwi-VTT kwaye iinguqulelo zokuqala zovavanyo zilindelekile ekwindla ka-2020.

“Njengokuba imeko yalo bhubhani isiya isiba mandundu kumazwe ngamazwe, siqalisile ukukhangela izisombululo kwingingqi yethu egqwesileyo. Sinamava kuphuhliso nakwimveliso ye-antibodies, kunye namava angaphambili kuyilo lweemvavanyo zokuqonda isifo. Yayisisigqibo esilula kuthi ukuba siqale ukusebenza kwi-antibody ye-COVID-19, utshilo uGqr Leena Hakalahti, inkokheli yeqela lophando lwe-VTT biosensor.

Uphando olwenziwe ngu-HUS Helsinki, isibhedlele saseyunivesithi, sidlala indima ebalulekileyo kuphuhliso lwe-antibodies kwaye iisampulu ezisetyenzisiweyo kuphando zithathiwe kwizigulana ezinesifo se-coronavirus.

Le projekthi yenziwa ngokubambisana ngokusondeleyo namaqela ophando akhokelwa ngunjingalwazi we-virology kwiYunivesithi yaseHelsinki, u-Olli Vapalahti kunye nomlawuli we-MeVac Vaccine Research Centre, unjingalwazi wezifo ezosulelayo kwiyunivesithi enye, u-Anu Kantele.

"Njengokuba uphando luqhubela phambili, siza kuvavanya ukuba kungenzeka na ukusebenzisa ii-antibodies eziphuhlisiweyo hayi kuvavanyo nje kuphela kodwa kunyango lwesifo se-coronavirus," utshilo uNjingalwazi Vapalahti.

I-VTT iqale uphando lokuvelisa ii-antibodies ezintsha ngokuchasene ne-anti-virus ye-SARS-CoV-2 ngenkxaso-mali yangaphakathi, kodwa iprojekthi ngoku ifuna ngononophelo inkxaso-mali eyongezelelweyo kunye namaqabane kuphuhliso lovavanyo olukhawulezileyo lolu vavanyo lukhawulezayo lwe-COVID-19. Ukuveliswa kovavanyo kunye nezixhobo zabo zohlalutyo kunokwenziwa eFinland ziinkampani ze-VTT kunye neFinland kwaye, ukongeza ekuhlangabezaneni neemfuno zangaphakathi, zinokuthengiswa kumazwe aphesheya.

“Ukonyusa amandla okwenza uvavanyo kudlala indima ebalulekileyo ekubekeni iliso kwisifo, kodwa iindlela zangoku zovavanyo zifuna ixesha elininzi kunye nezixhobo ezinciphisa amandla.

Injongo yovavanyo olukhawulezileyo kukuvumela ukukhula kwamandla okuvavanya kunye nokuqinisekisa ukubakho kweemvavanyo nangona ubhubhane uqhubeka, "utshilo usekela-mongameli wommandla wophando, uGqirha Jussi Paakkari we-VTT.

Sebenza kuvavanyo olukhawulezileyo ngoku ugxile ngokukodwa kwi-COVID-19, kodwa nje ukuba uvavanyo olukhawulezayo lwetekhnoloji ye-COVID-19 ichaziwe, inkqubo efanayo yophuhliso inokusetyenziswa ngokukhawuleza ekuchongeni ezinye iintsholongwane.

Ukuxilongwa kunye nempilo yedijithali zezona ndawo ziphambili kubuchwephesha be-VTT nabantu abamalunga nama-80 abasebenza kwimixholo enxulumene nayo eFinland kumaziko eOulu, Espoo, Tampere naseKuopio. I-VTT ikwanamava amaninzi ekuyileni izixhobo ezenzelwe ukufumanisa izifo kwizifo ezahlukeneyo.

Ipotifoliyo yetekhnoloji yeVTT ibandakanya yonke into efunekayo ukuphuhlisa izixhobo kunye neenkqubo zokuchonga ezinokulahlwa; iziko liyakwazi ukudibanisa ubuchule kwii-antibodies kunye noluhlu lwemveliso yemicu yovavanyo kunye nohlalutyo oluchanekileyo lwedatha.