Uphuhliso olutsha loNyango lweeMeko zeNeurological

I-Plexium, Inc. (i-Plexium) kunye ne-AbbVie zingene kwintsebenziswano yeqhinga elilodwa lokuphuhlisa kunye nokuthengisa inoveli ye-Targeted Protein Degradation (TPD) yonyango kwiimeko ze-neurological. Le ntsebenziswano idibanisa isakhono se-AbbVie se-neuroscience kunye neqonga le-TPD elibanzi le-Plexium elenza ukuba kufunyanwe iindlela zonyango ezintsonkothileyo ekujoliswe kuko kwimbali yamachiza.

"Ubambiswano lwethu kunye no-AbbVie lusivumela ukuba someleze isikhundla sethu sobunkokeli kwi-Targeted Protein Degradation kunye nokwandisa amandla ethu aphezulu kwi-class kwizifo ze-neurological," watsho uMongameli we-Plexium kunye ne-CEO uPercival Barretto-Ko. “I-Neuroscience yenye yezona ndawo zonyango zicela umngeni ekuphuhliseni amayeza amatsha, ngenxa yokuntsokotha kwezifo zesifo kunye nenani eliqingqiweyo leendlela eziye zaphumelela. Ngeqonga lethu elibanzi kunye nobuchule be-AbbVie kule ndawo, sikwimeko eyomeleleyo yokufumanisa intshayelelo entsha ngokuchasene nezinto ekujoliswe kuzo zexabiso eliphezulu ukuze ekugqibeleni siphucule ubomi bezigulana.

"Ukusebenzisana nePlexium ukuchonga kunye nokuqhubela phambili i-novel degraders ihambelana neenzame zika-AbbVie zokusebenzisa iteknoloji yeqonga lenoveli ukufuna unyango olusebenzayo kwizigulane eziphethwe zizifo eziphazamisayo ze-neurological," kusho u-Eric Karran, Ph.D., uSekela Mongameli, i-Neuroscience Discovery e-AbbVie. "I-AbbVie ihlala igxile kwinguquko yempembelelo yesigulana kunye nethekhnoloji entsha ethembisayo enokukhawulezisa uphuhliso lwezonyango ezintsha."

Ngaphantsi kwemigaqo yokubambisana, i-Plexium iya kuqhuba imisebenzi yophando lwangaphambili kwiithagethi zentsebenziswano, emva koko i-AbbVie inokhetho lokukhetha iinkqubo zophando olongezelelweyo kunye nemisebenzi yophuhliso. I-Plexium ifumene intlawulo yemali kwangaphambili kwaye ifanelekile ukufumana iintlawulo ezongezelelweyo ezivela kwa-AbbVie, kunye ne-royalty edibeneyo kwiimveliso ezithengiswayo, kwaye inokhetho lokuthatha inxaxheba kuphuhliso lwemveliso njengembuyekezo yemilinganiselo ephezulu ye-royalty. I-AbbVie iya kuba noxanduva lophuhliso kunye nokuthengiswa kwemveliso yehlabathi jikelele ngenxa yentsebenziswano.