I-Theranica, inkampani emiselweyo ye-digital therapeutics ephuhlisa i-electroceuticals ephezulu ye-migraine kunye nezinye iimeko zentlungu, namhlanje ibhengeze ukupapashwa kophando olutsha oluphononongwa ngoontanga olupapashwe kwi-Pain Medicine, ukuhlola ukusetyenziswa kokudibanisa iNerivio's® Guided Imagery, Education and Relaxation (GIER) -app yongenelelo olukhethwayo lokuziphatha kunyango oluqatha lwe-migraine.
Inqaku le-GIER yimodyuli ye-audio-visual software yemifanekiso ekhokelwayo, ukuphumla kunye nemfundo, eyilelwe ukusetyenziswa okukhethiweyo ngokubambisana nonyango lwe-REN. Ividiyo yemizuzu engama-25, edlalwa kwi-smartphone yomsebenzisi ngexesha lonyango lwe-REN, iquka iindlela ezintathu zokuphumla: ukuphefumla kwe-diaphragmatic, ukuphumla kwemisipha okuqhubekayo, kunye nemifanekiso ekhokelwayo, kunye nomxholo wemfundo yeentlungu kwi-migraine biology kunye nonyango lwe-REN. Izigulana zinokubukela kunye/okanye zimamele ividiyo xa iNerivio ivulelwe unyango oluqatha.
Uphononongo luhlolisise amaqela amabini ahambelana nezigulane ze-migraine. Elinye iqela lasebenzisa i-Nerivio, unyango olunxitywayo lwe-migraine, ngokwayo. Elinye iqela le-Nerivio + GIER longezelele unyango lwe-Nerivio ngenqaku elitsha le-GIER. Iziphumo ezivela kumdlalo olawulwa ngumdlalo, uphando lweengalo ezimbini lubonisa ukuba iqela le-Nerivio + GIER linenani eliphezulu lezigulane ezifumana ukukhululeka kwentlungu eqhubekayo, ukuphuculwa okuqhubekayo ekusebenzeni, kunye nokubuyela okuqhubekayo ekusebenzeni okuqhelekileyo, ngaphaya kwe-Nerivio yonyango yodwa.
"Kuqiniswa kakuhle ukuba ukungenelela kokuziphatha okufana nokuphefumula kwe-diaphragmatic, imifanekiso ekhokelwayo kunye neendlela zokuphumla zineenzuzo zokukhusela abantu abaphila ne-migraine," kusho uDkt Dawn Buse, uNjingalwazi weKlinikhi ye-Neurology e-Albert Einstein College of Medicine kunye nombhali wokuqala we funda. “Olu phononongo luye lwanceda ukuqinisekisa i-hypothesis yethu yokuba olu ngenelelo lunokunceda ngexesha lokuhlaselwa kwe-migraine. Ukuhlaselwa kwe-Migraine ngokuqhelekileyo kudibaniswa neentlungu zomzimba kunye neempawu ezongezelelweyo eziphazamisayo. Akumangalisi ke ngoko ukuba, olu didi lweempawu ludla ngokukhatshwa kukuxhalaba ngokweemvakalelo nangokwasemzimbeni kunye nonxunguphalo. Ukukhusela kwendalo "ukulwa okanye ukundiza" ukusabela kwenkqubo ye-nervous, ngelixa iinjongo ezintle, ngokwenene zichasene ngexesha lokuhlaselwa kwe-migraine. Imisebenzi yokuphumla inokubonelela ngentuthuzelo kunye nokunceda ukunciphisa uxinzelelo lwemisipha, ukukhuthaza ukujikeleza, kunye nokuhambisa umzimba kunye nengqondo ngokubanzi kwindawo ekhululekile kunye nekhululekile. Uphando lwethu lubonisa indlela eyandisa ngayo ibhokisi yesixhobo yesigulana eneempawu ezifana ne-GIER, ebandakanywe kwi-Nerivio app, enokuthi isetyenziswe ukuphucula izibonelelo zonyango ze-neurostimulation ngokuthomalalisa inkqubo ye-nervous ngelixa kwangaxeshanye kujongwa impilo-ntle yesigulana.
Idatha elindelekileyo evela kwizigulane ze-170, izigulane ezingapheliyo ze-migraine (okanye abantu abane-15 okanye ngaphezulu kweentsuku ezine-migraines ngenyanga), zahlaziywa (i-85 ngeqela ngalinye). I-79% yabasebenzisi kwiqela le-Nerivio + GIER bafumana ukukhululeka kwentlungu eqhubekayo (oko kukuthi, ukukhululeka kwentlungu ubuncinane kwi-50% yonyango), kanti i-57% yafumana kwiqela le-REN kuphela. I-71% yabasebenzisi kwiqela le-Nerivio + GIER bafumana ukuphuculwa okuqhubekayo komsebenzi (oko kukuthi, ukuphuculwa komsebenzi ubuncinane kwi-50% yonyango), xa kuthelekiswa ne-57% kwiqela le-REN kuphela. I-37.5% yabasebenzisi kwiqela le-Nerivio + GIER bafumana ukubuyiswa okupheleleyo okuqhubekayo ekusebenzeni ngokupheleleyo (okt, ubuncinane kwi-50% yonyango), xa kuthelekiswa ne-17.5% kwiqela le-REN kuphela. Lo mahluko phakathi kwamaqela wawubalulekile ngokwezibalo.
"Iqela lethu lophuhliso lwezonyango e-Theranica lizinikele ekuphuculeni rhoqo uncedo lwezigulane kwi-Nerivio, kwaye i-GIER ekhethiweyo iyingxenye yaloo mzamo," watsho uLiron Rabani, i-neuroscience Ph.D. kunye neNzululwazi eyiNtloko yeTheranica, owabhala ngokubambisana isifundo. "Ngelixa i-REN yangqinwa ukuba isebenza ngokwayo ekulweni neempawu ze-migraine, besicinga ukuba ukunceda abaguli baphumle kwaye baphucule impilo ngexesha le-migraine kunokuba nefuthe elongezelelweyo lonyango. Siyavuya ukuba olu phononongo lubonise ukuba luncedo kophuculo lwe-biobehavioral-mental-emotional ekuthomalaliseni iintlungu nokunceda izigulana zibuyele emsebenzini.”
I-Nerivio yindlela yonyango emiselweyo yokunxiba ehambisa i-Remote Electrical Neuromodulation (REN) ukuze isebenze umzimba wendalo we-Conditioned Pain Modulation mechanism ukunyanga intlungu kunye nezinye iimpawu ezinxulumene ne-migraine. Inxitywa kwingalo ephezulu kwaye ilawulwe nge-app kwi-smartphone yesigulana, ekwasebenza njengedayari ye-migraine.
INTO ONOKUYITHATHA KWELI NQAKU:
- Our research demonstrates how expanding the patient’s toolbox with features such as GIER, incorporated into the Nerivio app, can be utilized to enhance the therapeutic benefits of neurostimulation by calming the nervous system while at the same time addressing the patient’s wellbeing.
- I-Theranica, inkampani emiselweyo ye-digital therapeutics ephuhlisa i-electroceuticals ephezulu ye-migraine kunye nezinye iimeko zentlungu, namhlanje ibhengeze ukupapashwa kophando olutsha oluphononongwa ngoontanga olupapashwe kwi-Pain Medicine, ukuhlola ukusetyenziswa kokudibanisa iNerivio's® Guided Imagery, Education and Relaxation (GIER) -app yongenelelo olukhethwayo lokuziphatha kunyango oluqatha lwe-migraine.
- Results from the match-controlled, dual-arm study indicate the Nerivio+GIER group had a higher proportion of patients achieving consistent pain relief, consistent improvement in functioning, and consistent return to normal functioning, beyond that of Nerivio treatment alone.
