Emva kokuphonononga iingxelo ezingaphezu kwe-45,000 yabathathi-nxaxheba bolingo lweklinikhi, School Harvard Medical School abaphandi bathi uninzi lwe Isitofu se-covid-19 'iziphumo ebezingalindelekanga' abathi abantu bazifumana emva kwe-jab, ebangelwa kulindelo lwabantu hayi ngamayeza okugonya.
Abantu abaninzi bakhathazeke kakhulu Isitofu se-covid-19 'iziphumo ebezingalindelekanga' baziva ngenene nokuba bafumana i-placebo, uphando olutsha lubonisa.
Iziphumo ebezingalindelekanga ezahlukeneyo 'zenkqubo', ezinje ngentloko, ukudinwa, kunye neentlungu ezidibeneyo zixelwe kuzo zozibini iziqingatha zeqela lophando: ngabo bafumana amayeza okugonya e-COVID-19, nangabo bathe bengazi bafumene i-placebo.
Emva kokuhlalutya iingxelo, izazinzulu ezivela eBoston-based IBheteli yakwa-Deaconess Medical Centre bafikelele kwisigqibo sokuba into ebizwa ngokuba 'yisiphumo se-nocebo' - iimvakalelo ezingemnandanga ezibangelwa luxhala okanye ulindelo olubi - zibalelwa kwikota yesithathu yazo zonke iziphumo ebezingalindelekanga ezixeliweyo zesitofu sokugonya.
Ingxelo, eyapapashwa kwijenali ye-JAMA Network Open, ithi i-35% yabamkeli be-placebo babike iziphumo ezibi emva kwedosi yokuqala kunye ne-32% emva kweyesibini. Ngokuphawulekayo ngakumbi "iziganeko ezimbi" (AEs) zixelwe kumaqela okugonya, kodwa okubizwa ngokuba "iimpendulo ze-nocebo" zibalelwa "ngama-76% enkqubo ye-AEs emva kweyokuqala. Isitofu se-covid-19 idosi kunye ne-52% emva kwedosi yesibini.
Izazinzulu ziqaphela ukuba, nangona izizathu zokuthandabuza ugonyo "zahlukeneyo kwaye zintsonkothile," iinkxalabo malunga neziphumo ebezingalindelekanga ezivela kunyango. Izitofu ze-covid-19 "kubonakala ngathi yeyona nto iphambili" kwaye "iinkqubo zokugonya zikawonkewonke kufuneka zithathele ingqalelo ezi mpendulo ziphakamileyo ze-nocebo."
Enye ye School Harvard Medical School oonjingalwazi ababandakanyeka kuphando, bacacisa isayensi emva kwe "nocebo effect," bechaza ukuba "iimpawu ezingacacanga," ezinje ngentloko ebuhlungu kunye nokudinwa, zidweliswe kwiincwadana ezininzi zolwazi njengeziphumo ebezingalindelekanga ze-COVID-19.
"Ubungqina bucebisa ukuba olu hlobo lolwazi lunokubangela ukuba abantu bacinge ngokungafanelekanga iimvakalelo eziqhelekileyo zemihla ngemihla njengoko zivela kwisitofu sokugonya okanye zibangele ixhala kunye nexhala elenza abantu baqaphele iimvakalelo zomzimba malunga neziganeko ezimbi," watsho.
