I-CDC iqalise ukusebenzisana kwi-genomics yesizwe yentsholongwane

Amaziko aseMelika oLawulo noThintelo lweZifo, i-CDC, asungule umanyano lokudibanisa uthungelwano lwesizwe lweelebhu zokulandelelana eziya kukhawulezisa ukukhutshwa kwedatha yokulandelelana kwe-SARS-CoV-2 kwindawo kawonkewonke. Ukukhululwa ngokukhawuleza kwedatha yokulandelelana kwe-coronavirus evulekileyo kuya kunceda isikhokelo Covid-19 Impendulo yezempilo yoluntu, ukuqhuba izinto ezintsha kunye nokufumanisa, kunye nokuqonda kwangaphambili oku kunye nobhubhane wexesha elizayo.

le Ukulandelwa kwe-SARS-CoV-2 yokuPhendula ngokuNgxamisekileyo kwezeMpilo kaRhulumente, i-Epidemiology kunye nokuJongwa (i-SPHERES) Consortium, eya kuthi yandise kakhulu ukusetyenziswa kwe Ulandelelwano olupheleleyo lwe-genome (WGS) kwintsholongwane ye-COVID-19. I-SPHERES iya kubonelela ngokungaguquguqukiyo, ixesha lokulandelelana kwedatha kumaqela okuphendula ezempilo oluntu aphanda amatyala kunye namaqela e-COVID-19 kwilizwe liphela.

Eli qela litsha liza kubanceda baqonde ngcono ukuba inwenwa njani intsholongwane, kuzwelonke nakwindawo abahlala kuzo. Idatha engcono, nayo, iya kunceda amagosa ezempilo oluntu aphazamise ukuhanjiswa, kuthintele iimeko zokugula, kunye nokukhusela kunye nokusindisa ubomi.

“I-US yinkokeli yehlabathi kulandelelwano olukhawulezayo lwezixhobo zemfuzo. Le nzame ilungelelanisiweyo kulo lonke elabucala, labucala, iklinikhi, kunye neelebhu zempilo yoluntu ziya kudlala indima ebalulekileyo ekuqondeni usasazo, uguquko, kunye nonyango lwe-SARS-CoV-2. Ndiqinisekile ukuba iingqondo zethu ezigqwesileyo nezona zinobuchule zisebenza kunye ukusinceda ukusindisa ubomi namhlanje nangomso, utshilo uMlawuli we-CDC uRobert Redfield, MD

Ukulandelela intsholongwane ye-COVID-19 njengoko iguquka

Idatha yokulandelelana kweGenomic inokunika ukuqonda okungazange kubonwe ngaphambili kwi-biology ye-SARS-CoV-2, intsholongwane ebangela i-COVID-19, kwaye incede ekuchazeni imeko eguqukayo yesifo. Ngokulandelelanisa iintsholongwane ezivela kwi-United States, i-CDC kunye nezinye iziphathamandla zempilo yoluntu zinokuthi zibeke iliso kutshintsho olubalulekileyo kwintsholongwane kwaye zisebenzise olu lwazi ukukhokela umkhondo wokunxibelelana, iinzame zokunciphisa impilo yoluntu kunye neendlela zolawulo losulelo.

I-SPHERES Consortium ngumzamo wokulungelelanisa ukulandelelana kwe-SARS-CoV-2 kuzwelonke, uququzelela imizamo emincinci, imizamo yomntu ngamnye kuthungelwano olunye olusasazwayo lweelebhu, amaziko kunye nemibutho. Indibaniselwano idibanisa ubuchwephesha, itekhnoloji, kunye nezixhobo zamasebe ezempilo zikarhulumente angama-40 nakumakhaya, iilebhu ezinkulu zeklinikhi, nangaphezulu kwamaziko asebenzisanayo angaphezu kwamabini kurhulumente womanyano, kwizifundo nakwicandelo labucala.

I-SPHERES iya kuseka ezona ndlela zisebenzayo kunye nemigangatho yedatha yokuvumelana, ukukhawulezisa ukwabiwa kwedatha evulekileyo, kunye nokuseka iphuli yezixhobo kunye nobuchule bokunceda ukuzisa itekhnoloji yokuphelisa impendulo yesizwe ye-COVID-19.

Idatha ye-SPHERES ivuliwe, kwabelwana ngayo

Amalungu e-Consortium abelana ngokuzibophelela kukwabelana ngokulandelelana ngokukhawuleza okuvulekileyo. Baceba ukungenisa zonke iinkcukacha ezilandelelanayo ezilandelelanayo kwiindawo zokugcina zikawonkewonke kwiZiko leLizwe lezeMpilo kwiZiko leLizwe leNzululwazi ye-Biotechnology (i-NLM / NCBI), iGlobal Initiative ekwabelaneni ngeDatha yomkhuhlane weAvian (GISAID), kunye nolunye ugcino loluntu. Oku kuyakunceda ekuqinisekiseni ukuba idatha yokulandelelana kwentsholongwane e-United States ifumaneka ngokukhawuleza ekwenzeni izigqibo kwezempilo yoluntu kwaye ifikeleleke ngokukhululekileyo kubaphandi kuyo yonke indawo.

Amalungu e-Consortium abandakanya:

Iiarhente zaseburhulumenteni kunye neelebhu

Amaziko oLawulo lweNtsholongwane kunye noThintelo, iOfisi yoPhando oluPhezulu lweMolekyuli

ILebhu yeSizwe yeArgonne

I-Arhente yezeMpilo yoKhuselo, Usulelo lwehlabathi Izifo Ukuhlolwa

Ukutya kunye noLawulo lweeMithi

Lawrence Berkeley iLebhu kaZwelonke

ILebhu yeSizwe yaseLos Alamos

IZiko leLizwe lezeMpilo yoLwelwe kunye nezifo ezosulelayo, iOfisi yeGenomics kunye neTekhnoloji ePhambili

IZiko leLizwe leMigangatho kunye neTekhnoloji

ILayibrari yeSizwe yezeMpilo kwiZiko leLizwe leLwazi ngeBiotechnology

Iziko loPhando likaWalter Reed

Iilebhu zempilo zikarhulumente / zengingqi

Arizona

California

Delaware

District of Columbia

Florida

Hawaii

Maine

Maryland

Massachusetts

Michigan

Minnesota

North Carolina

North Dakota

Nevada

New Mexico

Inew york

Utah

Virginia

Washington

Wisconsin

Wyoming

Amaziko emfundo

IYunivesithi yaseBaylor

Cornell University

Iziko loPhando ngomhlaza kaFred Hutchinson

Isikolo seNtaba iSinayi sezoNyango

New York University

KwiNyuvesi yaseNorthern Arizona

IYunivesithi yaseBuffalo

IYunivesithi yaseCalifornia, eBerkeley

IYunivesithi yaseCalifornia, uDavis

IYunivesithi yaseCalifornia, i-Irvine

IYunivesithi yaseCalifornia, eLos Angeles

KwiYunivesithi yaseCalifornia, eSan Francisco

IYunivesithi yaseCalifornia, eSanta Cruz

University of Chicago

KwiYunivesithi yaseMaldan

KwiYunivesithi yaseMinnesota

KwiYunivesithi yaseNebraska

KwiYunivesithi yaseNew Mexico

Yunivesithi yaseWashington

Yunivesithi yaseYale

I Nkampani

Uxilongo lweAbbott

bioMerieux

Umbala weGenomics

IGingko Bioworks

IDbyDNA

Kwi-Q-Ifowuni

I-LabCorp

Ikhowudi enye

Iitekhnoloji zeOxford Nanopore

I-Biosciences yePacific

qiagen

Diagnostics

Ngokwenene iSayensi yoBomi

Amagama eenkampani abonelelwa ngeenjongo zolwazi kuphela, kwaye ukufakwa kwabo apha akuthethi ukuxhaswa kweenkampani okanye nayiphi na imveliso yazo yorhwebo okanye iinkonzo ngamaZiko aseMelika oLawulo lweNtsholongwane kunye noThintelo.

Impilo yoluntu okanye amaziko ophando angenzi nzuzo

Umbutho weelebhu zeMpilo kaRhulumente

ISiseko seBill kunye ne-Melinda Gates

IZiko elibanzi

UChan Zuckerberg BioHub

IZiko leCraig Venter

Umanyano lwezeMpilo kuLuntu lwe-Genomic Epidemiology

Izibhalo zoPhando

Ilabhoratri kaJackson

Inguqulelo yeZiko loPhando lweGenomics- eMantla

Isiseko seWalder

Kule minyaka mithandathu idlulileyo, iOfisi ye-CDC yeNkqubo yokuFunyanwa kweMolekyuli ePhakamileyo ityale imali kwiilabhoratri zempilo zikarhulumente nezikarhulumente ukwandisa ukusetyenziswa kwe-pathogen genomics kunye nezinye iitekhnoloji zelebhu eziphambili zophononongo lwezifo ezosulelayo kunye nokuphendula kwesifo. Utyalo-mali lwangoku lwe-Consortium lujolise ekusindiseni ubomi kubhubhane we-SARS-CoV-2 kunye nokulungiselela i-United States kunye nehlabathi ukuphendula kwindyikityha yexesha elizayo.

Ukufunda ngakumbi ngolandelelwano lwe-genomic okanye umsebenzi we-CDC ekufumaniseni okuphambili kweemolekyuli, ndwendwela https://www.cdc.gov/amd/